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Hyper symptoms but normal blood work?!?!

hypothyroid hyper symptoms tsh normal labs?

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#1 ALOHA

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Posted 10 February 2014 - 10:50 PM

Hi Everyone,

I have been diagnosed with autoimmune hypothyroidism a few years ago and have been taking Synthroid.  The past few weeks, I have been having very bad symptoms associated with hyperthyroidism, such as palpitations, severe insomnia, feeling hot, overheating during exercise while outdoors on a cold day, restlessness and trouble concentrating, etc.  I thought that I was for sure hyper due to too much synthroid, but my doctor said my lab results showed that I have a TSH of 2.3 and T3 and T4 are both normal.  

 

She thinks it could be from some other med I'm taking, but I somehow doubt it because I've been on all my other meds for a very long time and never had any of these symptoms.  The other meds I'm taking are Xopenex for asthma, Zyrtec, Flonaise, Xanax on occasion, Neurontin, and a couple of things for migraines as needed.  My doctor had my thyroid retested today (it was last tested a week ago) to make sure there wasn't a lab error.  I am seeing her again in two days.  Any help or ideas would be much appreciated.  I'm starting to get a little bit freaked out.  

 

Thank you.  



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Posted Today, 12:34 AM



#2 thumper54

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Posted 11 February 2014 - 04:03 AM

Welcome.  I'm sorry you are having problems.  I'm not an expert, but I have suffered from hypo symptoms for years and never tested high for TPO antibodies.  Recently though, I became hyper and I tested TSI antibodies myself as the doctor refused.  It was positive.  If you have Hashimotos it can include times of hyper.  You can have high TPO and also have TSI.  If you do have TSI, it can run the show causing the hyper feelings even when the TSH is higher than optimal. 



#3 Andros

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Posted 11 February 2014 - 04:52 PM

TSI
Normally, there is no TSI in the blood. If TSI is found in the blood, this indicates that the thyroid stimulating immunoglobulin is the cause of the of a person's hyperthyroidism.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
(Copy and paste into your browser) 

Trab
http://www.ncbi.nlm.nih.gov/pubmed/17684583
(Copy and paste into your browser) 

TBG (thyroxine binding globulin)  up, hypo............down, hyper
http://www.nlm.nih.gov/medlineplus/ency/article/003374.htm
(Copy and paste into your browser) 

Welcome to the board!

 

Well; as Thumper 54 has pointed out, it may be a very good idea for you to get TSI, TGB and Trab lab tests.  You will find info above.

 

Many of us have been hypo for a number of years and then flipped over to full-blown hyper!

 

I heartily recommend an ultra-sound as well if you have not had a recent one. 


The above is opinion only, not medical advice. No doctor degrees here. Please seek the advice of a qualified physician........ Andros :D

Graves' Disease, Lupus (Systemic & Discoid), Sjogren's and old age. ;) Armour........3 1/2 grains per day.

Welcome all members! Thank you everyone for participating on this board, for helping other posters and for sharing your experiences and wisdom!

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#4 Lovlkn

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Posted 12 February 2014 - 02:59 PM

 

I have a TSH of 2.3 and T3 and T4 are both normal.

ALOHA,

 

Can you please post your FT-4 and FT-3 labs with ranges.


Free T-4 and Free T-3 are absolutely necessary to properly dose yourself.
My experience is that 1/2 - 3/4 of range is your goal for optimal treatment

My Journey... 7 years to receive a diagnosis. TT 2004 after 4.5 years on Tapazole that had to be adjusted monthly - endo ran labs every 4 weeks. Remission was never going to happen for me so I opted for surgery to remove. Final DX by surgeon was Hashitoxicosis, TPO antibodies over 2000 and TSI 316% within the year prior to surgery. I never had a ultrasound or any lab testing to rule out cancer - pathology was negative. Post surgery I was kept hypo for many years - until I figured out how to dose my self, relying on where I fell in the FT-4 and FT-3 labs. I run TSH below range due to positive TBII antibodies. Horrible time adjusting to addition of Cytomel = patience pays off when adding this drug to the mix.

The happy ending ---> Stable dose since 1/10 Unithroid 125mcg, Cytomel 12.5mcg - labs I can live with.

None of the information on ThyroidBoards.com is intended to diagnose, treat, cure or prevent any disease. Information shared is based on my personal experiences and should not be considered medical advice. Please consult a physician before adjusting any medication.





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