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Can adding Cytomel to Synthroid Cause Hypothyroidism?

t3 t4 cytomel synthroid levothyroxine liothyronine suppress tsh add supplement

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#1 freebooter

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Posted 29 November 2018 - 05:37 PM

Group,

 

Here's my question -- Does anyone think adding 5mcg T3 to 75mcg T4 could cause hypothyroid symptoms?

 

Here's the background -- I take 75mcg of Synthroid/levothyroxine for hypothyroidism. I started feeling my thyroid symptoms recur about two months ago, and my doctor allowed me to add 5mcg of T3/Cytomel. This worked great for a while -- I felt less cold, had more energy, etc. But about a week or two ago I started feeling my symptoms recur, worse than ever. I am trying to figure out if this is simply a seasonal issue, or if adding the T3 could be causing the hypothyroid symptoms.

 

I ask this because an endocrinologist previously put me on 50mcg Cytomel *only*, which, within about 6 months, caused terrible hypothyroid symptoms, apparently due to the T3 "suppressing" my thyroid function.

 

Here are recent labs, which I don't think will be very helpful. Very small changes seem to cause big effects in me.

TSH: 1.160 (0.450-4.500)

T4 Free: 1.23 (0.82-1.77)

T3 Free: 3.3 (2.0-4.4)

 

Thus, my question, whether adding 5mcg of T3 to 75mcg T4 could cause hypothyroid symptoms, or if it seems more like a straightforward issue of needing more medication?

 

Thank you.

 

J.

 



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Posted Today, 07:04 AM



#2 Lovlkn

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Posted 29 November 2018 - 11:11 PM

Your goal is to fall somewhere between 1/2-3/4 of the range for both FT-4 and FT-3 when taking synthetic hormone.

Thyroid symptoms overlap for hypo and hyper.

Ferritin and D levels should be optimal for best results
Free T-4 and Free T-3 are absolutely necessary to properly dose yourself.
My experience is that 1/2 - 3/4 of range is your goal for optimal treatment

My Journey... 7 years to receive a diagnosis. TT 2004 after 4.5 years on Tapazole that had to be adjusted monthly - endo ran labs every 4 weeks. Remission was never going to happen for me so I opted for surgery to remove. Final DX by surgeon was Hashitoxicosis, TPO antibodies over 2000 and TSI 316% within the year prior to surgery. I never had a ultrasound or any lab testing to rule out cancer - pathology was negative. Post surgery I was kept hypo for many years - until I figured out how to dose my self, relying on where I fell in the FT-4 and FT-3 labs. I run TSH below range due to positive TBII antibodies. Horrible time adjusting to addition of Cytomel = patience pays off when adding this drug to the mix.

The happy ending ---> Stable dose since 1/10 Unithroid 125mcg, Cytomel 12.5mcg - labs I can live with.

None of the information on ThyroidBoards.com is intended to diagnose, treat, cure or prevent any disease. Information shared is based on my personal experiences and should not be considered medical advice. Please consult a physician before adjusting any medication.

#3 Pamzilla13

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Posted 30 November 2018 - 10:23 AM

Group,

 

 

 

I ask this because an endocrinologist previously put me on 50mcg Cytomel *only*, which, within about 6 months, caused terrible hypothyroid symptoms, apparently due to the T3 "suppressing" my thyroid function.

 

Do you happen to have labs for when you were taking Cytomel only? 

 

 

 

Here are recent labs, which I don't think will be very helpful. Very small changes seem to cause big effects in me.

TSH: 1.160 (0.450-4.500)

T4 Free: 1.23 (0.82-1.77)

T3 Free: 3.3 (2.0-4.4)

 

Your Free T3 is a tad low 3.5 to 3.7 would be more "optimal".

 

Perhaps you are reacting to a filler?...or it could be you are not "optimal" yet.

 

Have you tried natural thyroid hormone such as Armour or Nature-throid? 

 

I agree with Lovlkn that Vitamin D levels and ferritin should be optimal!!

 

 

 



#4 GOLGO13

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Posted 16 December 2018 - 05:58 PM

I wonder if it would be wise to get reverse T3 labs ordered in this case. Maybe reverse T3 is high and causing issues. I know it's a controversial lab though and your doctor may not agree to order it.


Original: TSH 71 TPO 1980

Levo 100 (March 2018): TSH 1.02 (range .5-4.5)....FT4 1.65 (range .82 to 1.77).

Levo 100 (April 2018): Felt terrible TSH .68

Levo 88 (May 29 2018): Felt better but low energy TSH 3.010 (.450-4.5)|Free T3 2.8 (2.0-4.4 pg/ml)| Free T4 1.50 (.82-1.77ng/dl) TPO 226

Levo 91 (equivalent) (July 16 2018): Felt sort of OK TSH 4.470 (.450-4.50)|Free T3 2.6 (2.0-4.4 pg/ml)| Free T4 1.44 (.82-1.77 ng/dl)|TPO 181

94 (half 88 and half 100) Best I have felt so far TSH 3.671 uIU/mL (0.350 - 5.000)| Free T4 1.14 ng/dL (0.70 - 1.25)| Free T3 2.2 pg/ml (1.7-3.7)

94 generic (Dec 2018) TSH 4.98...boo...

94 Synthroid (Feb 2019)Name Brand 6 days a week and 100 Sythroid one day a week TSH 4.829 uIU/mL (0.350 - 5.000 uIU/mL)| FT4 1.01 ng/dL (0.70 - 1.25 ng/dL)|FT3 2.6 pg/mL(1.7 - 3.7 pg/mL)

94 Synthroid (April 2019) 5 days a week, 100 twice a week TSH 2.763 uIU/mL (0.350 - 5.000 uIU/mL)| FT4 1.08 ng/dL (0.70 - 1.25 ng/dL)|FT3 2.5 pg/mL(1.7 - 3.7 pg/mL)

94 Synthroid (June 2019) 4 days a week, 100 3 days a week TSH 2.889 uIU/mL 0.350 - 5.000 uIU/mL| FT4 1.15 ng/dL 0.70 - 1.25 ng/dL|FT3  2.7 pg/mL 1.7 - 3.7 pg/mL

94 Synthroid (July 2019) 2 days a week, 100 5 days a week TSH 3.931 0.350 - 5.000 uIU/mL| FT4 1.07 ng/dL 0.70 - 1.25 ng/dL| FT3 2.4  pg/mL 1.7 - 3.7 pg/mL

100 Synthroid (Oct 2019) 7 days a week, 50 once a week TSH 2.479 0.350-5.000 uIU/mL| FT4 1.06 ng/dL 0.70 - 1.25 ng/d

100 Synthroid daily Synthroid 50 once a week TSH TSH 2.874 range .350 to 5 | T3 free 2.5 pg/ml range 1.7 to 3.7

112 Synthroid daily (Jan 2019) TSH 2.43 range .350-5.000 uIU/ml |  FT3 3.3 range 1.7-3.7 pg/mL | FT4 1.04 range .7-1.25 ng/Dl 

112 Synthroid Daily (Mar 2020)  TSH 2.069 range .350-5.000 uIU/ml |  FT3 2.8 range 1.7-3.7 pg/mL | FT4 1.08 range .7-1.25 ng/Dl (doing pretty good in general)

 

 






Also tagged with one or more of these keywords: t3, t4, cytomel, synthroid, levothyroxine, liothyronine, suppress, tsh, add, supplement

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